Primary

Abou-Donia, Mohamed B.

abou-doniaProfessor of Pharmacology and Cancer Biology
Professor of Neurobiology

Phone: 919.684.2221
Email: donia@duke.edu

Mechanisms of chemically induced neurodegenerative disorders.

Alvarez, James

alvarezAssistant Professor of Pharmacology and Cancer Biology

Phone: 919.681.5479
Email: james.alvarez@duke.edu

Mechanisms of tumor dormancy and recurrence.

 

 

Counter, Christopher M.

Chris CounterProfessor of Pharmacology and Cancer Biology
Associate Professor of Radiation Oncology

Phone: 919.684.9890
Email: chris.counter@duke.edu

The Counter lab studies the molecular signaling of the common oncogene RAS with the ultimate goal of developing new therapeutic approaches to target this signaling pathway.

Fox, Don

Assistant Professor of Pharmacology and Cancer Biology
Assistant Professor of Cell Biology

Phone: 919.613-8756
Lab Website

We study cells with extra chromosomes in repair of injured tissues, building organs, and disease.

Goetz, Sarah

Photo of Sarah GoetzAssistant Professor of Pharmacology and Cancer Biology

Phone: 919.684.3529
Email: sarah.c.goetz@duke.edu
Lab Website

We study the biology of primary cilia: tiny projections that function like antennae and allow cells to respond to signals from the surrounding environment. We are interested in the mechanisms that control cilium assembly as well as the role of ciliary signals in development and disease.

Haystead, Timothy A.J.

Tim HaysteadProfessor of Pharmacology and Cancer Biology

Phone: 919.613.8606
Email: timothy.haystead@duke.edu
Lab Website

My laboratory uses chemical biology based approaches to develop highly selective small molecule inhibitors targeting purine utilizing enzymes involved in various human diseases including various cancers, inflammatory diseases, hypertension, viral and other pathogenic infections.

Kastan, Michael B.

Michael KastanExecutive Director, Duke Cancer Institute
Professor of Pharmacology and Cancer Biology
Professor of Pediatrics

Phone: 919.684.3052
Email: michael.kastan@duke.edu

The Kastan lab studies stress response pathways in mammalian cells, particularly DNA damage signaling responses. Well known for contributions to our understanding of the p53 and ATM tumor suppressor genes, current activities also include development of novel therapeutics targeting signaling steps in stress response pathways.

Kuhn, Cynthia M.

Cindy Kuhn

Professor of Pharmacology and Cancer Biology
Professor in Psychiatry and Behavioral Sciences

Phone: 919.684.8828
Email: ckuhn@duke.edu

Adolescent onset of addiction, depression and eating disorders: the interaction of the development of monoamine systems, hormonal status and genetic sex.

Lew, Daniel J.

Daniel LewJames B. Duke Professor of Pharmacology and Cancer Biology
Professor of Genetics

Phone: 919.613.8627
Email: daniel.lew@duke.edu
Lab Website

We work on cell polarity, cell cycle control, and chemotropism (how cells can track chemical gradients).

Locasale, Jason

Jason LocasaleAssistant Professor of Pharmacology and Cancer Biology

Phone: 919.684.9309
Email: jason.locasale@duke.edu
Lab Website

Our lab is interested in understanding nutrition and metabolism and is focused in three closely connected areas: 1) Quantitative biology of metabolism, 2) The link between metabolism and chromatin biology/epigenetics, 3) Principles of dietary modulation and metabolic therapeutics in health and cancer.

MacAlpine, David

David MacAlpineAssociate Professor of Pharmacology and Cancer Biology
Director of Graduate Studies, Pharmacology

Phone: 919.681.6077
Email: david.macalpine@duke.edu
Lab Website

Mechanisms of genetic and epigenetic inheritance.

Mathey-Prevot, Bernard

Bernard Mathey-PrevotResearch Professor of Pharmacology and Cancer Biology
Professor of Pediatrics

Phone: 919.684.8043
Email: bernard.mathey-prevot@duke.edu

Signaling pathway activation kinetics and cell fate decisions in single cells.

McDonnell, Donald P.

Donald McDonnellGlaxo-Wellcome Professor of MCB and Chairman
Department of Pharmacology and Cancer Biology
Professor of Medicine

Phone: 919.684.6035
Email: donald.mcdonnell@duke.edu

Development and application of novel molecular approaches for the discovery of estrogen, progesterone and androgen receptor modulators for use in the treatment of prostate and breast cancer.

Newgard, Christopher B.

Chris NewgardProfessor of Pharmacology and Cancer Biology
Professor of Internal Medicine
Director, DMPI and Sarah W. Stedman Nutrition and Metabolism Center

Phone: 919.668.6059
Email: chris.newgard@duke.edu
Faculty Page

Metabolic regulatory mechanisms; Regulation of survival and function of pancreatic islets.

Pendergast, Ann Marie

Ann Marie PendergastAnthony R. Means Cancer Biology Professor of Pharmacology
and Cancer Biology
Vice Chair, Pharmacology and Cancer Biology

Phone: 919.681.8086
Email: ann.pendergast@duke.edu
Lab Website

Role of tyrosine kinase signaling networks in cancer metastasis and injury responses.

Schwartz-Bloom, Rochelle D.

Rochelle Schwartz-BloomProfessor of Pharmacology and Cancer Biology
Professor in Education
Professor in Psychiatry and Behavioral Sciences
Director, Undergraduate Studies in Pharmacology

Phone: 919.684.5181
Email: schwartz.bloom@duke.edu
RISE Website

Our research program includes science education curriculum development and assessment at the pre-college and undergraduate levels to demonstrate how pharmacology can help students learn biology and chemistry better.

Slotkin, Theodore

Theodore SlotkinProfessor of Pharmacology and Cancer Biology
Professor in Psychiatry and Behavioral Sciences
Professor in Neurobiology

Phone: 919.681.8015
Email: t.slotkin@duke.edu

Effects of endocrine status, environmental toxicants and drugs on brain development; molecular neurobiology of neuronal differentiation.

Thiele, Dennis J.

Dennis ThieleGeorge Barth Geller Professor of Pharmacology and Cancer Biology
Professor of Biochemistry
Professor of Molecular Genetics and Microbiology

Phone: 919.684.5776
Email: dennis.thiele@duke.edu
Lab Website

The Thiele lab investigates the role of Heat Shock Transcription Factors in health and disease and the role of copper as an antimicrobial weapon at the host-pathogen interface.

Wang, Xiao-Fan

Xiao-Fan WangDonald and Elizabeth Cooke Professor of Experimental Oncology
Professor of Pharmacology and Cancer Biology

Phone: 919.681.4861
Email: xiao.fan.wang@duke.edu

The primary interests of our research are mechanisms underlying cellular senescence and tumorigenesis.

Wood, Kris

Kris WoodAssistant Professor of Pharmacology and Cancer Biology

Phone: 919.613.8634
Email: kris.wood@duke.edu
Lab Website

Novel tumor vulnerabilities and systems-based strategies to overcome therapeutic resistance.

Yao, Tso-Pang

Tso-Pang YaoProfessor of Pharmacology and Cancer Biology
Associate Professor of Radiation Oncology

Phone: 919.613.8654
Email: tsopang.yao@duke.edu

We study the biology of the histone deacetylase, HDAC, family and the clinical utility of HDAC inhibitors.